Focus on key drivers of ageing.
There are currently over 720 million persons over the age of 65 globally which is expected to double by 2050 to >1.5 billion.¹ Diseases of ageing, including loss of mobility, metabolic dysfunction, and cognitive impairment increase with age and contribute dramatically to loss of healthspan and healthcare costs.
As we age we lose memory, strength and metabolic fitness. We can prevent these symptoms of ageing through discovery and development of preventative therapies. We pioneer deep learning to expand our understanding of fundamental ageing processes.
Brain
11-20% of people over 65 experience subjective cognitive decline resulting in >$300B in healthcare costs per year in the US alone. However some people can improve their symptoms with lifestyle modification, which indicates potential for new preventative therapies.²
Liver
The liver is a major driver of regulating the body’s metabolism, ensuring homeostatic energy balance and regulating immune and even brain activity. Approximately 1 in 4 adults globally have fatty liver disease (NAFLD) with increasing prevalence with age. While ageing reduces the liver’s regenerative capacity, this can be resolved through lifestyle choices.³
Muscle
Muscle strength decreases on average of 10% per decade after age 40. Loss of or reduced mobility with age contributes to nearly 3 million fall injuries among the elderly in the US alone, contributing to nearly $50B in healthcare costs. Loss of muscle, or sarcopenia, can be delayed or reversed by exercise.⁴
Changing the trajectory of health
to achieve rejuvenation.
